• free shipping on orders over $149*

  • we give back to our community

  • Buy now pay later with Afterpay


What You Need To Know About Pyrrole Disorder

03 December 2015

What is Pyrrole Disorder?

Pyrrole disorder goes by many names including the most common names, such as Pyroluria, Kryptopyrroles and other names used are Kryptopyrroluria, Pyrroluria, Pyrolle Disorder, Mauve Factor and Hemepyrrole.

This disorder can be described as the abnormal synthesis and metabolism of the oxygen carrying molecule in a person’s blood called haemoglobin. Pyrrole disorder is commonly found in individuals suffering from the following disorders:

  • Depression
  • Anxiety disorder
  • Oppositional Defiant Disorder (ODD)
  • Schizophrenia
  • Bipolar disorder
  • Attention Deficit Hyperactivity Disorder (ADHD)


Perfect Supplements Australia


This disorder has been linked with an increase of pyrroles (hydroxyhemopyrrolin-2-one or HPL) in urine and severe deficiencies of zinc, Biotin, Omega 6 Fat GLA and pyridoxine (Vitamin B6) in the body.

Symptoms of Pyrrole Disorder vary but may include:

  • Poor stress control
  • Elevated kryptopyrroles in urine
  • Sensitivity to bright lights
  • Morning nausea
  • Tendency to delay or skip breakfast
  • Very dry skin
  • Pale skin, inability to tan
  • History of underachievement
  • Little or no dream recall
  • Autoimmune disorders
  • Poor growth
  • Coarse eyebrow hair
  • Stretch marks on skin
  • Fear of airplane travel
  • Obsessions with negative thoughts
  • Delayed puberty
  • Dark or mauve-coloured urine
  • Affinity for spicy and salty foods
  • Abnormal fat distribution
  • Delicate facial features
  • Extreme mood swings
  • History of reading disorder
  • Severe inner tension
  • Frequent infections
  • Premature greying of hair
  • Abnormal or absent menstrual periods
  • Poor muscle development
  • “fruity” breath and/or body odour
  • Spleen-area pain
  • Severe anxiety
  • Histrionic behaviour
  • Joint pains
  • Poor wound healing psoriasis
  • Tendency to stay up very late
  • Mental issues (anxiety, paranoia, schizophrenia, OCD, Bipolar etc.)


Perfect Supplements Australia

Causes of Pyrrole Disorder

Diet and lifestyle are major contributors that can lead a person to suffer with pyrrole disorder. Research shows that if anyone in a person’s family had suffered from alcoholism and mental disorders, a person is at a greater risk of developing pyrrole disorder.

Other causes are:

  • Poor dietary choices
  • Poor digestive health
  • Leaky Gut Syndrome 
  • Stress
  • Dysbiosis (gut flora out of balance) - an overgrowth of detrimental bacteria or Candida an overgrowth of fungal spores in the intestinal tract
  • Alcohol, smoking and drugs
  • Trauma

Importance of the Pyrrole Diet

Zinc and Vitamin B6 are important for neurotransmitter production in the body. Neurotransmitters such as serotonin or the happy hormone, melatonin or sleep hormone, GABA or relaxation hormone and acetyl choline (for the memory)

Zinc and Vitamin B6 also play an important role in the production of steroid hormones like cortisol or the anti inflammatory, antihistamine and stress hormone) and it converts oils found in the body. Oils such as EPA/DHA and mostly GLA (eicosapentaenoic acid, docosahexaenoic acid and gamma-linolenic acid) are all low in people with pyrrole’s disorder and can be damaged by the oxidative stress or toxins produced by pyrrole.

Perfect Supplements Australia



Pyrrole’s disorder can be treated through Zinc and Vitamin C restoration and replacement therapy. It must be provided in an efficient way where it can be absorbed easily like in a supplement form for the body to absorb it fast and it must be in the right dosage. Please do not self-diagnose, always go to a highly qualified and recommended naturopath as many doctors don’t recognise this illness but are beginning to catch on.

Remember, it’s YOUR health, don’t leave it in the hands of others who may not have your best interest at heart. I know in the past I have personally fired many doctors and had heated arguments with them over natural health and healing. Don’t take what they say as gospel EVER, they are not trained in health, wellbeing or nutrition (well for the majority anyways), they are trained in human anatomy & physiology, diseases and medication and do not get me wrong- doctors are a necessary part of society but just make sure you know the difference with what they can offer and what alternative practitioners can offer you.

Perfect Supplements Australia



*Disclaimer: the information in this article is intended purely as information and not health advice. It is not intended to treat, diagnose, prevent or cure and one should always seek expert advice from their trusted health practitioner.




The Blog

Unlock Vitality with Cordyceps Mushrooms
10 July 2024

Unlock Vitality with Cordyceps Mushrooms

Why Zinc is Essential for Women's Health and Well-being
02 July 2024

Why Zinc is Essential for Women's Health and Well-being

ZinCerola: Why it Should it Be In Everyone's Supplement Stack
19 June 2024

ZinCerola: Why it Should it Be In Everyone's Supplement Stack